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Supercooled storage preserves high-energy adenylate pools Total adenylate pools (total concentration of adenine nucleotides within a cell) and associated purine catabolism/salvage are modulated by oxidative stress 48

CKIP-1 affects the polyubiquitination of Nrf2 and Keap1 via mediating Smurf1 to resist HG-induced renal fibrosis in GMCs and diabetic mice kidneys

276 While AD has genetic causes, notably the apolipoprotein E4 (ApoE4) allele, which promotes the accumulation of A plaques through the MAPK signaling pathway, 277 the majority of cases are sporadic and strongly age-associated

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